After accidents, cancer is the second leading cause of death in children ages 1 to 14. Because of major treatment advances in recent decades, 85% of children with cancer now survive 5 years or more. Still, survival rates can vary a great deal depending on the type of cancer and other factors. The American Cancer Society uses a comprehensive approach to working to end childhood cancer as we know it, for everyone, by leveraging our unique strengths in funding the best research; publishing the most current trends in childhood cancer occurrence and survival; providing information on symptoms, early detection, treatment and support for children with cancer and their families; and working to improve the quality of life for childhood cancer patients and survivors.